Alamar Biosciences Completes $80M Series B Fundraising to Bring Unprecedented Performance to the Proteomics Market

Fremont, CA, September 8, 2021 (PR NEWSWIRE) — Alamar Biosciences, Inc., a precision
proteomics company that brings both ultra-high sensitivity and massively parallel scale to
proteomic analysis, announced today that it has closed its $80 million Series B financing round,
bringing its total funding to $110 million. The Series B financing round was led by Sherpa
Healthcare Partners and included Morningside Ventures, Samsara Biocapital, and existing
investors Qiming Venture Partners and Illumina Ventures.

This oversubscribed round of investment will accelerate the development of Alamar’s
proprietary proteomics platform, which will be the most sensitive, highly multiplexed, and high
dynamic range solution for life science research, pharmaceutical development, and diagnostics
such as liquid biopsy. The platform leverages Next Generation Sequencing to bring the power of
genomics to proteomics, enabling the early detection of cancer and other diseases.

“We are very pleased to have these top-tier investors supporting our next phase of
development. They bring tremendous amount of expertise in life sciences and diagnostics,
which will be extremely valuable to us as we build the company,” said Dr. Yuling Luo, Founder,
Chairman and CEO. “Despite recent progress in the field, there is still no technology that unites
two essential goals in proteomics analysis, namely the ability to go as deeply as possible to
detect very low abundance proteins and the ability to profile thousands of proteins in a single
sample. This capability will be critical for the discovery and measurement of many proteins in
human plasma that are currently undetectable. Alamar’s NULISA and Attobody platforms will
help fill this void and will drive a new wave of innovations in research, diagnostics, and

Alamar Biosciences was founded by Dr. Luo, a technologist and serial entrepreneur who
previously founded Advanced Cell Diagnostics (ACD), now a part of Bio-Techne, and led it as
President and CEO. At ACD he pioneered the field of spatial genomics together with Dr. XiaoJun
Ma by inventing and successfully commercializing RNAscope, the world’s most sensitive
RNA in situ detection technology. Recognizing a similar critical need for ultra-sensitive protein
detection technology in proteomics, Dr. Luo started Alamar Biosciences with Dr. Steve Chen,
who was also a co-founder of ACD, and Dr. Yiyuan Yin, a structural biologist with extensive
antibody engineering expertise.

The Alamar Biosciences team has applied their insights gained from developing single-molecule
detection technologies and antibody engineering to create two technology platforms –
NULISATM and AttobodyTM . The combination of these ground-breaking platforms provides the
unique ability to detect extremely low levels of protein biomarkers in human blood plasma, and
to do so in a high-plex format allowing for the measurement of thousands of protein targets in
a single assay, leading to a new generation of noninvasive precision diagnostics.

“Alamar has made great strides in developing its novel technologies. This financing will position
Alamar to complete the development of its platform and will help position the company for its
commercial launch,” said Nick Naclerio, Founding Partner of Illumina Ventures.

“We are thrilled to partner with the Alamar team to fully develop their game-changing platform
and provide researchers around the globe with the tools they need to unlock the full potential
of proteomics,” commented Darren Cai, Founder and Managing Partner of Sherpa Healthcare

“We are pleased to continue our support of Alamar, which has made excellent progresses in the
past two years. With three potential lines of business – research instruments and reagents,
diagnostics, and antibody therapeutics – we believe the company is well-positioned to make a
significant impact on the future of healthcare,” said Amy Tang, Venture Partner of the
company’s Series A lead investor, Qiming Venture Partners.

About Alamar Biosciences
Alamar Biosciences is a privately held life sciences company with a mission to transform the
field of proteomics to enable the early detection of cancer and other diseases. The company’s
two proprietary technology platforms, NULISA™ and Attobody™, work seamlessly with the
latest advances in genomics to achieve single-digit attomolar detection sensitivity, greatly
surpassing the most sensitive protein detection technology on the market today. The
Attobodies have picomolar affinity and built-in high specificity and have the potential to expand
antibody therapeutics to many targets intractable with conventional antibodies. For more
information, please visit