Advancing Alzheimer’s Disease Detection with Brain-Derived pTau217 Assays

January 20, 2026
Online
8:00 am PT / 11:00 am ET / 4:00 pm GMT
Topic:
Neurology

Presenters

  • Prof. Jonathan Schott
    Chief Medical Officer - Professor of Neurology - Group Leader
    Alzheimer’s Research UK - University College London - UKDRI
  • Alex Forrest-Hay
    Senior Vice President, Sales
    Alamar Biosciences

Summary

In this webinar, Jonathan Schott and Alex Forrest-Hay will showcase how new biomarker assays for brain-derived pTau217 capture disease-relevant changes earlier and with greater resolution.

Amyloid plaques and Tau tangles are a key pathological feature of Alzheimer’s Disease (AD), and increased phosphorylated Tau217 (pTau217) levels have proven to be a robust biomarker for this condition. Measuring brain-derived pTau from plasma samples with high sensitivity and specificity is shown to improve the accuracy of detecting AD and reduce the percentage of samples in the indeterminant range.

In this webinar, brought to you by Alamar Biosciences, Jonathan Schott and Alex Forrest-Hay will discuss the latest ultra-sensitive assays for measuring brain-derived pTau217 and outline how they are transforming the detection and prediction of AD.

Topics to be covered

  • The role of brain-derived biomarkers in improving AD detection
  • The development and performance of high-sensitivity nucleic acid-linked immuno-sandwich assays for CNS disease
  • Comparison of assay performance to standard assays in real-world samples

Steve Williams, MD, PhD

CSO

Dr. Willams serves as the company’s Chief Scientific Officer. He was previously Chief Medical Officer at Standard Biotools and at SomaLogic where he pioneered the discipline for discovery and validation of predictive, diagnostic and prognostic models using machine-learning applied to large-plex proteomics. 20 such tests were used for drug characterization, safety and efficacy when incorporated in clinical drug trials at Pharma/Biotech and 17 different multivariate tests were validated and translated into regulated healthcare uses. Prior to SomaLogic, Dr. Williams was at Pfizer in the UK and the USA as a clinical triallist in Translational Medicine, and subsequently as VP, Global Clinical Technology. He sat on the National Advisory Council for the National Institute of Biomedical Imaging and Bioengineering, the Executive Committee for the FNIH Biomarkers Consortium, and worked with FDA and PhRMA on developing evidentiary standards for biomarker qualification. Dr. William’s medical training was in London, at Charing Cross and Westminster Medical School, followed by a PhD in medicine/physiology at the same institution and training in Radiology at the University of Newcastle Upon Tyne. Steve is co-inventor on 26 proteomics patents and author/coauthor on multiple foundational proteomics manuscripts.

Justin McAnear

CFO

Mr. McAnear serves as the company’s Chief Financial Officer. He brings over 25 years of operational and financial leadership experience across various sectors and was instrumental in taking 10x Genomics public in 2019, serving as its CFO for over five years. Mr. McAnear served for over 3 years as Tesla’s VP of Worldwide Finance and Operations, supporting landmark initiatives such as the Model X and Model 3 launches and Solar City acquisition.  He also held various roles at Apple and J&J earlier in his career and served as a naval officer and aviator for over 9 years.