Inflammatory Protein Signatures Associated with Proneness to Early Life Infection and Asthma

Featuring:

Jessica Lasky-Su, DSc, MS

Associate Professor in Medicine and Associate Statistician,
Harvard Medical School and Brigham and Women’s Hospital

 

Alex Forrest-Hay

VP of Sales
Alamar Biosciences

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Immune development in early life is critical for establishing a trajectory toward long-term health; however, little is understood about how early-life inflammation may impact immune development.

In this webinar, Jessica Lasky-Su, associate professor in medicine at Harvard Medical School and Brigham and Women’s Hospital, will discuss a study in which she and colleagues measured 203 inflammatory protein targets across 180 samples from healthy children at ages 1 and 6 using Alamar Biosciences’ NULISAseq Inflammation panel. The team identified the inflammatory proteins at age 1 that were associated with proneness to infection and the development of asthma by age 6. They also characterized critical changes in the inflammatory profile that developed among those with infection proneness and asthma by age 6. Finally, they assessed the impact of sex on these findings. 

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Steve Williams, MD, PhD

CSO

Dr. Willams serves as the company’s Chief Scientific Officer. He was previously Chief Medical Officer at Standard Biotools and at SomaLogic where he pioneered the discipline for discovery and validation of predictive, diagnostic and prognostic models using machine-learning applied to large-plex proteomics. 20 such tests were used for drug characterization, safety and efficacy when incorporated in clinical drug trials at Pharma/Biotech and 17 different multivariate tests were validated and translated into regulated healthcare uses. Prior to SomaLogic, Dr. Williams was at Pfizer in the UK and the USA as a clinical triallist in Translational Medicine, and subsequently as VP, Global Clinical Technology. He sat on the National Advisory Council for the National Institute of Biomedical Imaging and Bioengineering, the Executive Committee for the FNIH Biomarkers Consortium, and worked with FDA and PhRMA on developing evidentiary standards for biomarker qualification. Dr. William’s medical training was in London, at Charing Cross and Westminster Medical School, followed by a PhD in medicine/physiology at the same institution and training in Radiology at the University of Newcastle Upon Tyne. Steve is co-inventor on 26 proteomics patents and author/coauthor on multiple foundational proteomics manuscripts.

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Justin McAnear

CFO

Mr. McAnear serves as the company’s Chief Financial Officer. He brings over 25 years of operational and financial leadership experience across various sectors and was instrumental in taking 10x Genomics public in 2019, serving as its CFO for over five years. Mr. McAnear served for over 3 years as Tesla’s VP of Worldwide Finance and Operations, supporting landmark initiatives such as the Model X and Model 3 launches and Solar City acquisition.  He also held various roles at Apple and J&J earlier in his career and served as a naval officer and aviator for over 9 years.