NULISA™ Dried Blood Spot Extraction Kit

From Spot to Signal. Standardize proteomics from microsamples.

The NULISA™ DBS Extraction Kit provides a standardized, high-throughput workflow for recovering protein analytes from dried blood and dried plasma spots.  Combined with NULISA’s attomolar sensitivity, the kit unlocks high-quality multiplexed proteomic data from minimally invasive, remotely collected samples. 

Built for High-Quality Multiplexed Data

  • 85–95% target detectability across NULISAseq panels on most devices tested. 
  • 96-sample filter-plate format for high-throughput processing. 
  • 4+ validated microsampling devices with a device-agnostic protocol. 

Standardized Extraction Workflow

A validated, ready-to-use reagent kit with buffer, filter plates, collection plates, and plate seals. 

Device-Agnostic Compatibility

One workflow, multiple device options. Optimized across leading microsampling 
devices including C
apitainer, Telimmune, Mitra, and Tasso.
 

High-Throughput Format

96-well filter-plate format scales to large population health, clinical, and translational research studies. 

High Detectability from Microsamples

85-95% target detectability across CNS and Inflammation panels on most devices tested. 

Enables Remote and Longitudinal Designs

Supports ambient-shipped, minimally invasive samples. Reaches populations and settings where traditional venipuncture is not feasible. 

Built for the NULISA Platform

Pairs the kit’s standardized extraction with NULISA’s attomolar sensitivity for multiplexed protein measurement from a single small-volume sample. 

Device-agnostic

Compatible with Leading Microsampling Devices

One extraction workflow, validated across the devices your studies already use.

Simple. Repeatable. scalable.

The DBS Extraction Workflow

Five steps from microsample to NULISA-ready extract. The filter-plate format is built for routine 96-well processing. 

Step 1

Take the dried blood spot discs (Telimmune, Capitainer, or other collection devices) and transfer them onto a 96-well filter plate.

Step 2

Stack the collection plate below the extraction filter plate and secure with lab tape.

Step 3

Add NULISA DBS Extraction Buffer.

Step 4

Seal the plate and agitate the filter plate stack and centrifuge.

Step 5

Collect the samples in the collection plate and store until ready to be tested.

Where it fits

Studies and Settings Where DBS Changes What's Possible

Longitudinal and At-Home Studies
Frequent self-collection from a fingerstick. Capture biomarker dynamics over time without burdening participants.

Translational and Clinical Research
Standardized sample prep means reproducible data across sites. Scale studies without sacrificing assay performance.

Pediatric and Vulnerable Populations
Minimally invasive collection opens access to populations where venipuncture is impractical.

Global and Remote Cohorts
Ambient-stable samples remove the cold chain. Study geographies that were previously out of reach.

Discovery and Biomarker Programs
Pair the kit with NULISA CNS, Neuro 220, and Inflammation panels for multiplexed protein measurement at attomolar sensitivity.

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Steve Williams, MD, PhD

CSO

Dr. Willams serves as the company’s Chief Scientific Officer. He was previously Chief Medical Officer at Standard Biotools and at SomaLogic where he pioneered the discipline for discovery and validation of predictive, diagnostic and prognostic models using machine-learning applied to large-plex proteomics. 20 such tests were used for drug characterization, safety and efficacy when incorporated in clinical drug trials at Pharma/Biotech and 17 different multivariate tests were validated and translated into regulated healthcare uses. Prior to SomaLogic, Dr. Williams was at Pfizer in the UK and the USA as a clinical triallist in Translational Medicine, and subsequently as VP, Global Clinical Technology. He sat on the National Advisory Council for the National Institute of Biomedical Imaging and Bioengineering, the Executive Committee for the FNIH Biomarkers Consortium, and worked with FDA and PhRMA on developing evidentiary standards for biomarker qualification. Dr. William’s medical training was in London, at Charing Cross and Westminster Medical School, followed by a PhD in medicine/physiology at the same institution and training in Radiology at the University of Newcastle Upon Tyne. Steve is co-inventor on 26 proteomics patents and author/coauthor on multiple foundational proteomics manuscripts.

Justin McAnear

CFO

Mr. McAnear serves as the company’s Chief Financial Officer. He brings over 25 years of operational and financial leadership experience across various sectors and was instrumental in taking 10x Genomics public in 2019, serving as its CFO for over five years. Mr. McAnear served for over 3 years as Tesla’s VP of Worldwide Finance and Operations, supporting landmark initiatives such as the Model X and Model 3 launches and Solar City acquisition.  He also held various roles at Apple and J&J earlier in his career and served as a naval officer and aviator for over 9 years.