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SciNeuro Pharmaceuticals and Alamar Biosciences Collaborate to Discover Novel Therapeutic Antibodies for CNS Diseases

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  • February 15, 2022
  • Fremont, CA and Rockville, MD
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Alamar Biosciences (Alamar), a platform company focused on transforming the field of proteomics to enable the early detection of cancer and other diseases, and SciNeuro Pharmaceuticals (SciNeuro), a leader in the discovery and development of innovative therapeutics for the treatment of neurological diseases, announced a multi-program collaboration and license agreement to discover and develop novel therapeutic antibodies for targets selected by SciNeuro within the field of neurological diseases, based on Alamar’s Attobody platform.

“We are excited about our collaboration with Alamar to discover novel therapeutic antibodies for SciNeuro’s CNS programs,” commented Dr. Min Li, Founder and CEO of SciNeuro. “Alamar’s Attobody platform has already successfully generated promising antibodies against targets selected by SciNeuro. We look forward to continuing our collaboration with Alamar to discover novel therapeutic candidates.”

Alamar’s proprietary Attobody™ platform produces a highly diverse pool of antibodies with singledigit picomolar affinity and exquisite specificity. Compared to traditional antibody engineering, the Attobody platform deploys an accelerated antibody design and engineering process to generate novel antibodies without the need for affinity maturation.

Dr. Yuling Luo, Founder, Chairman & CEO of Alamar, commented: “We are thrilled to work with SciNeuro to discover additional novel antibodies for their drug discovery programs, building on our initial success. Antibody therapeutics are increasingly deployed against cancer, infectious diseases and neurological disorders, and their success critically depends on optimal affinity and specificity.

Our Attobody technology optimizes these two key attributes, and can improve success rates for a broad range of targets including traditionally intractable targets such as GPCRs and ion channels. We plan to actively exploit the potential of this powerful technology in therapeutic applications.”

Under the terms of the agreement, SciNeuro will have exclusive, worldwide rights to develop and commercialize therapeutic antibodies resulting from the collaboration. Alamar will receive research payments and is eligible to receive from SciNeuro downstream clinical and commercial milestone payments and royalties on net sales of resulting products.

About Alamar Biosciences
Alamar Biosciences is a privately held life sciences company with a mission to transform the field of proteomics to enable the early detection of cancer and other diseases. The company’s two proprietary technology platforms, NULISA™ and Attobody™, work seamlessly with the latest advances in genomics to achieve single digit attomolar detection sensitivity, greatly surpassing the most sensitive protein detection technology on the market today. The Attobodies have picomolar affinity and built-in high specificity and have the potential to expand antibody therapeutics to many targets intractable with conventional antibodies. For more information, please visit www.alamarbio.com.

About SciNeuro Pharmaceuticals
SciNeuro Pharmaceuticals is an innovation-driven, neuroscience-focused biopharmaceutical company with corporate and R&D facilities located in China and the United States. The company has established a broad portfolio of novel therapeutic candidates to address neurodegenerative and other CNS diseases. SciNeuro focuses on targets that are supported by human biology and which play a critical role in regulating foundation biology, to achieve better probability of success in clinical development. SciNeuro is committed to delivering medicines that can make a difference to improve the lives of patients around the world, transforming scientific discoveries into groundbreaking therapies. To learn more, visit https://scineuro.com/.

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Steve Williams, MD, PhD

CSO

Dr. Willams serves as the company’s Chief Scientific Officer. He was previously Chief Medical Officer at Standard Biotools and at SomaLogic where he pioneered the discipline for discovery and validation of predictive, diagnostic and prognostic models using machine-learning applied to large-plex proteomics. 20 such tests were used for drug characterization, safety and efficacy when incorporated in clinical drug trials at Pharma/Biotech and 17 different multivariate tests were validated and translated into regulated healthcare uses. Prior to SomaLogic, Dr. Williams was at Pfizer in the UK and the USA as a clinical triallist in Translational Medicine, and subsequently as VP, Global Clinical Technology. He sat on the National Advisory Council for the National Institute of Biomedical Imaging and Bioengineering, the Executive Committee for the FNIH Biomarkers Consortium, and worked with FDA and PhRMA on developing evidentiary standards for biomarker qualification. Dr. William’s medical training was in London, at Charing Cross and Westminster Medical School, followed by a PhD in medicine/physiology at the same institution and training in Radiology at the University of Newcastle Upon Tyne. Steve is co-inventor on 26 proteomics patents and author/coauthor on multiple foundational proteomics manuscripts.

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Justin McAnear

CFO

Mr. McAnear serves as the company’s Chief Financial Officer. He brings over 25 years of operational and financial leadership experience across various sectors and was instrumental in taking 10x Genomics public in 2019, serving as its CFO for over five years. Mr. McAnear served for over 3 years as Tesla’s VP of Worldwide Finance and Operations, supporting landmark initiatives such as the Model X and Model 3 launches and Solar City acquisition.  He also held various roles at Apple and J&J earlier in his career and served as a naval officer and aviator for over 9 years.