NULISA Platform

Unlocking the Proteome

The NULISA™ Platform sets a new standard in proteomic analysis with attomolar sensitivity, allowing for unprecedented biomarker detection and quantitation.  

By leveraging a proprietary sequential immunocomplex capture and release mechanism and the latest advances in Next Generation Sequencing (NGS), the NULISA technology provides both ultra-high sensitivity and scalable multiplexing. 

Low abundant Protein Biomarkers require high sensitivity detection

ULTRA HIGH SENSITIVTY

Raising the Bar by Lowering the Limit (of Detection)

Ultra-high attomolar sensitivity and lower limits of detection for the discovery and detection of critical biomarkers.  

BROAD DYNAMIC RANGE

Measuring Changes Across the Biological Spectrum

With single plex up to 7 logs and multiplex up to 12 logs of dynamic range, NULISA enables quantitation across a broad range of biological expression levels without the need for dilution.

FLEXIBLE PLEX

Scaling from Single-plex
to Multiplex

Flexible, scalable chemistry provides the ability to focus in on a single target, or multiplex hundreds to potentially thousands of targets in a single sample on one platform.

NULISA assays maintain performance from single qPCR to multiplex NGS analyses.

Fully Automated Workflow

Single-plex results in <6 hours and multiplex results in <15 hours with <30 minutes of hands-on time with the ARGO™ System

Single-plex Workflow

Simple, robust and reproducible with
<30 min hands-on time
Simple, robust and reproducible with
<30 min hands-on time
High throughput sample-to-results in <6 hours run time
High throughput sample-to-results in <6 hours run time
Automated,
cloud-based analytics
Automated,
cloud-based analytics

Multiplex Workflow

Simple, robust and reproducible with
<30 min hands-on time
Simple, robust and reproducible with
<30 min hands-on time
High throughput sample to pooled NGS library in <6 hours run time
High throughput sample to pooled NGS library in
<6 hours run time
8 hours sequencing run on illumina systems
8 hours sequencing run on illumina systems
Automated,
cloud-based analytics
Automated,
cloud-based analytics

FOR RESEARCH USE ONLY. Not for use in diagnostic procedures. 

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