Neurodegenerative Disease Biomarker Detection Using an Ultra-Sensitive Profiling Method

Webinar

Neurodegenerative Disease Biomarker Detection Using an Ultra-Sensitive Profiling Method

Featuring:

Henrik Zetterberg, MD, PhD

Professor of Neurochemistry
University of Gothenburg

 

Doug Hinerfeld, PhD 

Senior Director of Application Support
Alamar Biosciences

Brain-derived biomarkers of neurodegenerative diseases are important targets for new therapies. In the context of Alzheimer’s disease, scientists are exploring the use of protein biomarkers for early diagnosis, screening, prognosis prediction, and disease monitoring. But these markers are often present at very low concentrations in plasma or serum, much too low for most existing proteomics assays to detect and measure.

In this GEN webinar, Henrik Zetterberg, MD, PhD, an expert in Alzheimer’s disease, will discuss his efforts to discover and validate blood-based biomarkers for various CNS disorders. During his presentation, he will share data from his evaluation of the NULISA immunoassay platform’s ability to detect biomarkers of Alzheimer’s disease from serum. You will also hear from Doug Hinerfeld, PhD, who will discuss the NULISA platform’s multiplex and protein marker detection capabilities in more depth.

Steve Williams, MD, PhD

CSO

Dr. Willams serves as the company’s Chief Scientific Officer. He was previously Chief Medical Officer at Standard Biotools and at SomaLogic where he pioneered the discipline for discovery and validation of predictive, diagnostic and prognostic models using machine-learning applied to large-plex proteomics. 20 such tests were used for drug characterization, safety and efficacy when incorporated in clinical drug trials at Pharma/Biotech and 17 different multivariate tests were validated and translated into regulated healthcare uses. Prior to SomaLogic, Dr. Williams was at Pfizer in the UK and the USA as a clinical triallist in Translational Medicine, and subsequently as VP, Global Clinical Technology. He sat on the National Advisory Council for the National Institute of Biomedical Imaging and Bioengineering, the Executive Committee for the FNIH Biomarkers Consortium, and worked with FDA and PhRMA on developing evidentiary standards for biomarker qualification. Dr. William’s medical training was in London, at Charing Cross and Westminster Medical School, followed by a PhD in medicine/physiology at the same institution and training in Radiology at the University of Newcastle Upon Tyne. Steve is co-inventor on 26 proteomics patents and author/coauthor on multiple foundational proteomics manuscripts.

Justin McAnear

CFO

Mr. McAnear serves as the company’s Chief Financial Officer. He brings over 25 years of operational and financial leadership experience across various sectors and was instrumental in taking 10x Genomics public in 2019, serving as its CFO for over five years. Mr. McAnear served for over 3 years as Tesla’s VP of Worldwide Finance and Operations, supporting landmark initiatives such as the Model X and Model 3 launches and Solar City acquisition.  He also held various roles at Apple and J&J earlier in his career and served as a naval officer and aviator for over 9 years.